ASTM-E1373:2001 Edition

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E1373-01 Standard Test Method for Conducting a Subchronic Inhalation Toxicity Study in Rats

Published By	Publication Date	Number of Pages
ASTM	2001	5

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Category: ASTM

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Description

ASTM E1373-01

Historical Standard: Standard Test Method for Conducting a Subchronic Inhalation Toxicity Study in Rats

ASTM E1373

Scope

1.1 This test method determines the no observed-effect level (NOEL) and toxic effects associated with continuous or repeated inhalation exposure to a chemical, pesticide, or mixture for a period of 90 days. The test is not capable of determining those effects that have a long latency period for development (for example, carcinogenicity and life shortening).

1.2 This test method which is applicable to a gas, vapor, aerosol, or particulate is conducted after initial information on toxicity is obtained by acute testing.

1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

Keywords

aerodynamic diameter; blood chemistry; cumulative toxicity; geometric mean diameter; geometric standard deviation; head-only exposure; hematology; histopathology; inhalable diameter; inhalation; inhalation chamber; median diameter; nasal exposure; necropsy; particle size distribution; pesticide; rat; subchronic; toxicity; urinalysis

ICS Code

ICS Number Code 07.080 (Biology. Botany. Zoology)

DOI: 10.1520/E1373-01

PDF Catalog

PDF Pages	PDF Title
1	Scope Referenced Documents Terminology
2	Significance and Use Hazards
3	Test Animals Facilities Concentrations Levels Procedure
4	Quality Assurance Interpretation of Results Report Precision and Bias
5	Keywords

Additional information

Standard Title	E1373-01 Standard Test Method for Conducting a Subchronic Inhalation Toxicity Study in Rats
Published Code	ASTM
Publication Date	2001
Pages Count	5