HPS N13.22-2013

$15.60

Bioassay Programs for Uranium

Published By	Publication Date	Number of Pages
HPS	2013	79

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Category: HPS

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Description

This standard provides bioassay program requirements for
long-lived uranium isotopes (half-life greater than
²³⁴U), including criteria for determining:

a) the conditions requiring bioassay;

b) the selection of individuals to be included in a bioassay
program;

c) the sampling and measurement frequencies; and

d) the action levels and corresponding actions that are
appropriate for different compounds, measurements, and sampling
frequencies.

Procedures for quality assurance and records requirements are
provided in other bioassay program standards, and in applicable
federal, state, and local regulations.

The appendices to this standard are not a part of the standard.
However, they provide the bases and rationale for the quantitative
provisions of the standard. They are also provided to assist in
establishing bioassay programs by presenting technical information,
procedures, and literature references that are helpful in
developing the sample collection and analytical procedures
necessary to bioassay programs. The appendices also include
guidance for the estimation of internal radiation doses from
bioassay data, and methods of estimating internal chemical
exposures for comparison with toxic limits.

This standard does not specify preferred chemical, radiometric,
or in-vivo counting procedures for measuring uranium. This standard
also does not specify quantitative performance criteria for the
accuracy and precIsion of analytical or measurement procedures;
another standard is referenced for these criteria.

Purpose

This standard provides criteria for establishing and managing a
bioassay program to monitor and evaluate intakes from uranium,
distributions of uranium within the body following intake, and the
resulting radiation doses or possible chemical effects. Action
levels are also provided in terms of measured bioassay quantities,
in order to help ensure, for various uranium compounds and isotopic
enrichments, that exposure to workers from internally deposited
uranium will be maintained below acceptable limits.

Additional information